A stillborn fetus with alpha thalassemia major has the appearance on peripheral blood smear shown here. Note that predominantly hemoglobin Bart's results in marked anisocytosis and poikilocytosis of RBC's, with expansion of erythropoiesis and presence of many immature RBC's in the peripheral blood, as evidenced by polychromasia, nucleated RBC's and even erythroblasts seen here.